Benefits of a New, Nonsystemic Lipid-Lowering Agent: The Clinician's Perspective
نویسندگان
چکیده
منابع مشابه
Formulation and Evaluation of Nanocrystals of a Lipid Lowering Agent
Atorvastatin calcium, the lipid lowering agent, is taken as a model drug characterized by poor water solubility and bioavailability. In this study an attempt was made for preparation of nanocrystals using high pressure homogenization. A number of stabilizers were included as well as polymers at different concentrations, and the formulations were homogenized for ten cycles at a pressure of 1000 ...
متن کاملFormulation and Evaluation of Nanocrystals of a Lipid Lowering Agent
Atorvastatin calcium, the lipid lowering agent, is taken as a model drug characterized by poor water solubility and bioavailability. In this study an attempt was made for preparation of nanocrystals using high pressure homogenization. A number of stabilizers were included as well as polymers at different concentrations, and the formulations were homogenized for ten cycles at a pressure of 1000 ...
متن کاملformulation and evaluation of nanocrystals of a lipid lowering agent
atorvastatin calcium, the lipid lowering agent, is taken as a model drug characterized by poor water solubility and bioavailability. in this study an attempt was made for preparation of nanocrystals using high pressure homogenization. a number of stabilizers were included as well as polymers at different concentrations, and the formulations were homogenized for ten cycles at a pressure of 1000 ...
متن کاملBenefits of statins beyond lipid lowering
Increasing evidence has accumulated suggesting that inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, or statins, have therapeutic ‘pleiotropic’ effects independent of cholesterol lowering. These include anti-inflammatory and antioxidative properties, improvement of endothelial function and increased nitric oxide bioavailability. In addition to elucidating underlying mech...
متن کاملFormulation and Evaluation of Nanocrystals of a Lipid Lowering Agent
Atorvastatin calcium, the lipid lowering agent, is taken as a model drug characterized by poor water solubility and bioavailability. In this study an attempt was made for preparation of nanocrystals using high pressure homogenization. A number of stabilizers were included as well as polymers at different concentrations, and the formulations were homogenized for ten cycles at a pressure of 1000 ...
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ژورنال
عنوان ژورنال: Preventive Cardiology
سال: 2001
ISSN: 1520-037X,1751-7141
DOI: 10.1111/j.1520-037x.2001.00811.x